Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutation and telomerase reactivation

Table 2 The correlations between p53, Rb, c-myc, hTERT, bcl-2 and H. pylori in benign diseases and gastric cancer

H. pylori	CG		IMI-II		IMIII		DysI-II		DysIII		GC
	+(31)	-(11)	+(32)	-(14)	+(16)	-(9)	+(30)	-(18)	+(17)	-(10)	+(48)	-(36)
c-myc	5	0	7	1	10a	1	18a	4	13a	3	44	30
bcl-2	3	0	12	5	9a	1	17	7	13	5	38	17
p53	0	0	2	1	3	2	12a	2	6	4	39	25
Rb	3	0	4	0	6	2	11	3	9	3	40a	21
P53-Rb	3	0	4	1	6	3	21a	4	15a	3	48a	28
hTERT	0	0	1	0	4	0	8	2	9	3	47a	30

^aP < 0.05 vs the non-infected group.