Mechanism of 5-fluorouracil required resistance in human hepatocellular carcinoma cell line Bel7402

Figure 2 FLU accumulation in Bel₇₄₀₂ and Bel₇₄₀₂/5-FU cells. The cells were incubated with 100 μmol·L^-1 FLU for 3hr. After washing, the cells were trypsinized and intracellular fluorescence of FLU was determined with a flow cytometer. Data were pooled from three independent experiments. ^bP < 0.001 vs Bel₇₄₀₂ cells