Relationship between Egr-1 gene expression and apoptosis in esophageal carcinoma and precancerous lesions

Table 3 The relationship between the protein expression of Bcl-X_L and cell apoptosis in esophageal precancerous lesions and cancer tissues

Groups	n	Bcl-XL positive		Bcl-XL negative
		n (%)	AI(cells/mm2)	n (%)	AI(cells/mm2)
Normal epithelia	39	4 (10.3)	1.4 ± 1.2	35 (89.7)	8.3 ± 4.3
Simple hyperplasia	52	11 (21.2)	3.7 ± 3.6	41 (82.0)	14.5 ± 3.7
Dysplasia	41	28 (68.3)a	18.9 ± 8.2b	13 (31.7)	20.6 ± 6.3
Carcinoma in situ	2	1 (50.0)	11.8 ± 3.3	1 (50.0)	29.0 ± 5.7
Invasive carcinoma	64	46 (71.9)	14.5 ± 7.5c	18 (28.1)	28.6 ± 8.6

^aP < 0.01, χ² = 28.06 vs normal epithelia, χ² test;

^bP < 0.01, t = 10.53 vs normal epithelia, Student’s t test;

^cP < 0.01, t = 6.10 vs com-pared with Bcl-X/_L protein negative group, Student’s t test.