Relationship between Egr-1 gene expression and apoptosis in esophageal carcinoma and precancerous lesions

Table 2 The relationship between the expressions of Egr-1 and cell apoptosis in esophageal precancerous lesions and cancer tissues

Groups	n	Egr-1 positive		Egr-1 negative
		n (%)	AI(cells/mm2)	n (%)	AI(cells/mm2)
Normal epithelia	39	9 (23.1)	10.2 ± 4.1	30 (76.9)	3.8 ± 2.5
Simple hyperplasia	52	20 (38.5)	16.4 ± 5.6	30 (60.0)	7.2 ± 4.3
Dysplasia	41	27 (65.9)a	25.4 ± 9.2b	14 (34.1)	10.9 ± 7.4
Carcinoma in situ	2	1 (50.0)	29.3 ± 5.6	1 (50.0)	11.5 ± 3.7
Invasive carcinoma	64	17 (26.6)c	30.8 ± 6.8	47 (73.4)	21.4 ± 9.1

^aP < 0.01, χ² = 14.78 vs normal epithelia, χ² test;

^bP < 0.01, t = 6.80 vs normal epithelia, Student’s t test;

^cP < 0.01, χ² = 15.84 vs Dysplasia, χ² test.