Relationship between Egr-1 gene expression and apoptosis in esophageal carcinoma and precancerous lesions

Table 1 Changes of cell apoptosis in esophageal precancerous lesions and cancer tissues

Groups	n	Apoptosis cases (%)	AI (cells/mm2)
Normal epithelia	39	8 (20.5)	8.2 ± 3.1
Simple hyperplasia	52	17 (32.7)	13.4 ± 4.3
Dysplasia	41	31 (75.6)a	17.8 ± 8.3b
Carcinoma in situ	2	2 (100)	20.3 ± 5.1
Invasive carcinoma	64	64 (100)	25.2 ± 9.8

^aP < 0.01, χ² = 24.29 vs normal epithelia, χ² test;

^bP < 0.01, t = 5.19 vs normal epithelia, Student’s t test.