Transfection of colorectal cancer cells with chemokine MCP-3 (monocyte chemotactic protein-3) gene retards tumor growth and inhibits tumor metastasis

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Dec 15, 2002 (publication date) through Nov 4, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Liver Cancer

World J Gastroenterol. Dec 15, 2002; 8(6): 1067-1072
Published online Dec 15, 2002. doi: 10.3748/wjg.v8.i6.1067

Table 1 Tumor size in the mice inoculated with CMT93 or its gene transfectants (cm², ^-x±s)

Days after tumor injection	Tumor size in the mice inoculated with
Days after tumor injection	CMT93	CMT93/mock	CMT93/MCP-3
5	0.181 ± 0.020	0.170 ± 0.012	0.097 ± 0.012^a
10	0.398 ± 0.030	0.397 ± 0.025	0.186 ± 0.019^a
15	0.720 ± 0.185	0.751 ± 0.157	0.372 ± 0.104^a
20	0.950 ± 0.303	0.954 ± 0.309	0.416 ± 0.167^a
25	1.385 ± 0.222	1.335 ± 0.292	0.699 ± 0.170^a
30	1.769 ± 0.371	1.680 ± 0.643	1.021 ± 0.253^a

^aP < 0.05 vs CMT93 or CMT93/mock group

Citation: Hu JY, Li GC, Wang WM, Zhu JG, Li YF, Zhou GH, Sun QB. Transfection of colorectal cancer cells with chemokine MCP-3 (monocyte chemotactic protein-3) gene retards tumor growth and inhibits tumor metastasis. World J Gastroenterol 2002; 8(6): 1067-1072
URL: https://www.wjgnet.com/1007-9327/full/v8/i6/1067.htm
DOI: https://dx.doi.org/10.3748/wjg.v8.i6.1067