Clinical Research
Copyright ©The Author(s) 2002.
World J Gastroenterol. Oct 15, 2002; 8(5): 943-946
Published online Oct 15, 2002. doi: 10.3748/wjg.v8.i5.943
Table 1 Univariate analysis of the clinicopathologic factors for the survival of 86 patients with bile duct carcinoma
FactorsNo. of patientsP value
Sex0.90
Male51
Female35
Age (yrs)0.33
< 5029
≥ 50570.15
Location of tumor
Upper40
Middle13
Lower33
Size of tumor0.21
< 2 cm11
2 – 4 cm62
> 4 cm13
Macroscopic type of lesions0.43
Papillary17
Nodular32
Infiltrating37
Histological type of lesion0.02
Papillary adenocarcinoma7
Well differentiated adenocarcinoma27
Moderately differentiated adenocarcinoma36
Poorly differentiated adenocarcinoma14
Adenosquamous cell carcinoma2
Hepatic metastasis0.88
Present2
Absent84
Lymph node metastasis0.02
Present37
Absent49
Hepatic invasion0.36
Present29
Absent57
Pancreatic invasion0.004
Present21
Absent65
Duodenal invasion0.005
Present14
Absent72
Resected margin of the bile duct0.03
Present19
Absent67
Perineural invasion0.01
Present65
Absent21
Vascular invasion0.04
Present17
Absent69
Depth of cancer invasion0.04
Invasion limited to fibromuscular layer9
Invasion limited to adventitia and subserosal layer59
Invasion to and beyond the serosal exposure18