Expression of exogenous rat collagenase in vitro and in a rat model of liver fibrosis

doi:10.3748/wjg.v8.i5.901

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Oct 15, 2002 (publication date) through Nov 11, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 15, 2002; 8(5): 901-907
Published online Oct 15, 2002. doi: 10.3748/wjg.v8.i5.901

Table 2 Effects of in vivo transfection of FLAG-tagged rat collagenase on the accumulation of collagen type I and III in experimental liver fibrosis

Group	n	ILD of collagen I	ILD of collagen III
A	6	17.35 ± 2.62	18.94 ± 3.78
B	6	86.83 ± 11.93^a	75.21 ± 10.07^a
C1	7	69.25 ± 12.31^a^b	62.10 ± 9.72^a^b
C2	7	72.18 ± 14.18^a^b	64.80 ± 11.69^a^b

^aP < 0.05 when compared with normal control group (group A);

^bP < 0.05 when compared with disease control group (group B). ILD: Integral Light Density; N: number of rats in each group

Citation: Wang JY, Guo JS, Yang CQ. Expression of exogenous rat collagenase in vitro and in a rat model of liver fibrosis. World J Gastroenterol 2002; 8(5): 901-907
URL: https://www.wjgnet.com/1007-9327/full/v8/i5/901.htm
DOI: https://dx.doi.org/10.3748/wjg.v8.i5.901