Mutational characteristics in consecutive passage of rapidly replicating variants of hepatitis A virus strain H2 during cell culture adaptation

Table 3 One-step growth dynamics of HAVH2K7P22 on KMB17 cells

Post inoculation days	Antigen titers	Infectious titers (LgCCID50/mL)
2	1:8	ND*
4	1:16	6.0
6	1:32	6.67
8	1:128	7.17
10	1:512	7.5
12	1:1024	7.8
14	1:1024	7.17
16	1:1024	7.0
18	1:1024	7.0
20	1:1024	6.83
22	1:1024	7.0
24	1:1024	6.8
26	1:2048	6.5

*Not determined