Mutational characteristics in consecutive passage of rapidly replicating variants of hepatitis A virus strain H2 during cell culture adaptation

Table 2 Titers of different passages of HAVH2K7 on KMB17 for 14 d.

Passages	Antigen titers	Infectious titers (LgCCID50/mL)
1	1:16	5.83
2	1:8	5.5
3	1:16	5.67
4	1:32	6.0
5	1:32	6.5
6	1:64	6.77
7	1:64	6.67
8	1:64	6.5
9	1:64	6.67
10	1:128	6.83
11	1:128	7.0
12	1:256	7.0
13	1:256	7.17
14	1:256	7.0
15	1:256	7.17
16	1:256	7.0
17	1:512	7.17
18	1:512	7.33
19	1:512	7.5
20	1:512	7.67
21	1:1024	7.67
22	1:1024	7.83