Hepatoprotective role of ganoderma lucidum polysaccharide against BCG-induced immune liver injury in mice

Table 1 Effect of Ganoderma lucidum polysaccharide (GLP) on the weight of liver and the activity of serum alanine transaminase (ALT) in BCG-induced immune hepatic injury in mice (¯x ± s)

Group	Liver weight (g)	ALT (U·L-1)
Control	0.99 ± 0.16	22.03 ± 10.99
BCG (125 mg·kg-1)	1.79 ± 0.24b	245.18 ± 41.03b
BCG (125 mg·kg-1) + LPS (125 μg·kg-1)	1.84 ± 0.14b	285.88 ± 23.81bc
BCG (125 mg·kg-1) + GLP (25 mg·kg-1)	1.78 ± 0.20b	236.86 ± 27.94b
BCG (125 mg·kg-1) + GLP (50 mg·kg-1)	1.57 ± 0.18bc	189.81 ± 43.99bc
BCG (125 mg·kg-1) + GLP (100 mg·kg-1)	1.28 ± 0.20bd	178.78 ± 13.16bd
BCG (125 mg·kg-1) + GLP (200 mg·kg-1)	1.41 ± 0.43bc	208.18 ± 27.93bc

^aP < 0.05,

^bP < 0.01 compared with control.

^cP < 0.05,

^dP < 0.01 compared with BCG-pretreated group. n = 9 mice (liver weight groups) or 10 mice (ALT groups).