Expression of focal adhesion kinase and α5 and β1 integrins in carcinomas and its clinical significance

Table 1 Expression of FAK and integrin subunits α5 and β1 in human gastric carcinomas and their relation to clinical and histological variables

	FAK		Integrin α5		Integrin β1
	-/+	++/+++	-/+	++/+++	-/+	++/+++
Type of tissues
Unaffected margin specimen	49	2	12	39	8	43
Gastric carcinoma	32	43	53	22	56	19
	P < 0.01		P < 0.01		P < 0.01
Differentiation
Poor	14	30	36	8	37	7
Moderate or well	18	13	17	14	19	12
	P < 0.05		P < 0.05		P < 0.01
Extent of invasion
Mucosa or superficial stratum	13	3	11	5	12	4
Deep or full stratum	19	40	42	17	44	15
	P < 0.01		NS		NS
Metastasis
Absent	23	13	26	10	29	7
Present	19	30	27	12	27	12
	P < 0.01		NS		NS

NS: No significant