Effects of histone acetylation and DNA methylation on p21WAF1 regulation

doi:10.3748/wjg.v8.i3.400

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Jun 15, 2002 (publication date) through Nov 20, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 15, 2002; 8(3): 400-405
Published online Jun 15, 2002. doi: 10.3748/wjg.v8.i3.400

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Figure 3 Butyrate, TSA, TPX and Apicidin inhibits HDAC enzyme activity, and HAT from p300/CBP, P/CAF and GCN5 resulting in histone hyperacetylat ion of H3 or H4 associated p21^WAF1 gene, and induces transcriptional activation of the p21^WAF1 gene.

Citation: Fang JY, Lu YY. Effects of histone acetylation and DNA methylation on p21^WAF1 regulation. World J Gastroenterol 2002; 8(3): 400-405
URL: https://www.wjgnet.com/1007-9327/full/v8/i3/400.htm
DOI: https://dx.doi.org/10.3748/wjg.v8.i3.400