Cloning of cytochrome P-450 2C9 cDNA from human liver and its expression in CHL cells

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Apr 15, 2002 (publication date) through Nov 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 15, 2002; 8(2): 318-322
Published online Apr 15, 2002. doi: 10.3748/wjg.v8.i2.318

Table 1 Nomenclature and characteristics of CYP2C9 alleles

Allele	Protein	Nucleotide changes	Effect	Enzyme activity		Ref.
Allele	Protein	Nucleotide changes	Effect	In vivo	in vitro	Ref.
CYP2C91*	CYP2C9.1	None		Normal	Normal	3
CYP2C92*	CYP2C9.2	430C > T	R144C		Decr	36
CYP2C93*	CYP2C9.3	1075A > C	I359L	Decr	Decr	37, 38, 39, 43
CYP2C94*	CYP2C9.4	1076T > C	I359T			42, 43
CYP2C95*	CYP2C9.5	1080C > G	D360E	Decr		44
CYP2C96*		818delA	frame shift	Decr		45
CYP2C97-12						In press

Citation: Zhu GJ, Yu YN, Li X, Qian YL. Cloning of cytochrome P-450 2C9 cDNA from human liver and its expression in CHL cells. World J Gastroenterol 2002; 8(2): 318-322
URL: https://www.wjgnet.com/1007-9327/full/v8/i2/318.htm
DOI: https://dx.doi.org/10.3748/wjg.v8.i2.318