Copyright
©The Author(s) 2002.
World J Gastroenterol. Apr 15, 2002; 8(2): 318-322
Published online Apr 15, 2002. doi: 10.3748/wjg.v8.i2.318
Published online Apr 15, 2002. doi: 10.3748/wjg.v8.i2.318
Allele | Protein | Nucleotide changes | Effect | Enzyme activity | Ref. | |
In vivo | in vitro | |||||
CYP2C9*1 | CYP2C9.1 | None | Normal | Normal | 3 | |
CYP2C9*2 | CYP2C9.2 | 430C > T | R144C | Decr | 36 | |
CYP2C9*3 | CYP2C9.3 | 1075A > C | I359L | Decr | Decr | 37, 38, 39, 43 |
CYP2C9*4 | CYP2C9.4 | 1076T > C | I359T | 42, 43 | ||
CYP2C9*5 | CYP2C9.5 | 1080C > G | D360E | Decr | 44 | |
CYP2C9*6 | 818delA | frame shift | Decr | 45 | ||
CYP2C9*7-*12 | In press |
- Citation: Zhu GJ, Yu YN, Li X, Qian YL. Cloning of cytochrome P-450 2C9 cDNA from human liver and its expression in CHL cells. World J Gastroenterol 2002; 8(2): 318-322
- URL: https://www.wjgnet.com/1007-9327/full/v8/i2/318.htm
- DOI: https://dx.doi.org/10.3748/wjg.v8.i2.318