Basic Research
Copyright ©The Author(s) 2002.
World J Gastroenterol. Apr 15, 2002; 8(2): 318-322
Published online Apr 15, 2002. doi: 10.3748/wjg.v8.i2.318
Table 1 Nomenclature and characteristics of CYP2C9 alleles
AlleleProteinNucleotide changesEffectEnzyme activity
Ref.
In vivoin vitro
CYP2C9*1CYP2C9.1NoneNormalNormal3
CYP2C9*2CYP2C9.2430C > TR144CDecr36
CYP2C9*3CYP2C9.31075A > CI359LDecrDecr37, 38, 39, 43
CYP2C9*4CYP2C9.41076T > CI359T42, 43
CYP2C9*5CYP2C9.51080C > GD360EDecr44
CYP2C9*6818delAframe shiftDecr45
CYP2C9*7-*12In press