Pharmacokinetics of radioimmunotherapeutic agent of direct labeling mAb 188Re-HAb18

Table 4 Effect of various concentration of SnCl₂ and GH on free ¹⁸⁸ReO₄ amounts, colloid amounts and labeling efficiency

Concentration		188ReO-4	Colloid	Labelingfficiency(%)
aSnCl2 (g·L-1)	8	0.3	3.6	90.9
	4	0.4	2.8	90.1
	2	9.7	2.1	82.7
	1	21.8	1.2	71.2
bGH (mol·L-1)	0.8	1.1	1.1	91.7
	0.4	12.5	2.5	78.8
	0.2	16.6	2.8	72.7
	0.1	20.6	4.1	71.3

^aMolar ratio of 2-ME: F(ab’)₂ = 400:1,Concentration of GH = 0.5 mol·L^{-1 b}Molar ratio of 2-ME: F(ab’)₂ = 400:1,Concentration of SnCl₂ = 2 g·L^-1