The management of patients with the short bowel syndrome

Table 1 The effect of small bowel resection on intestinal peptides that are known regulate intestinal growth

Factor	Source	Effect of Small Bowel Resection on Factor
Epidermal Growth	Salivery glands and Brunner’s glands in the jejunum	EGF levels are increased in saliva and diminished in urine 3 d after resection in mice[11].
Factor (EGF)
Enteroglucagon	L cells of ileum and colon	12 d after a 75% small bowel resection there was a significant increase in concentration of enteroglucagon in the plasma of rats[12].
Glucagon-like	L cells of ileum and colon	There is an increase in expression of GLP-2 mRNA in the ileum of rats after small bowel resection[13].
Peptide 2 (GLP-2)
		There is a decrease in expression of dipeptidyl peptidase IV mRNA, the enzyme that inactivates GLP-2, in the ileum of rats after small bowel resection[14].
Insulin-like Growth	Cells of the small	80% small bowel resection led to a 183% and 249% increase in IGF-1 mRNA in the jejunum and ileum respectively of rats[15].
factor-1 (IGF-1)	intestine
Peptide tyrosine	L cells of ileum	After 70% resection in rats the concentration of PYY in plasma was elevated for at least 2 wk and there was a
tyrosine (PYY)		four and six-fold increase in PYY mRNA in ileum and colon at six hours after resection[14].
Neurotensin	Gut mucosal endocrine cells
	(N cells) in the jejunum and ileum	50% resection of the distal intestine in dogs was associated with a transient increase in neurotensin[16].