Chiral metabolism of propafenone in rat hepatic microsomes treated with two inducers

doi:10.3748/wjg.v7.i6.830

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Dec 15, 2001 (publication date) through Jan 23, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 15, 2001; 7(6): 830-835
Published online Dec 15, 2001. doi: 10.3748/wjg.v7.i6.830

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Figure 1 Chiral high performance liquid chromatogram of racemic propafenone in rat liver microsomal incubates after 30 min incubation. A: BNF pre-treated B: without incubation. Peaks 1, 2: Diastereomers of S(+)-propafenone and R(-)-propafenone; Peaks 3, 4: Diastereomers of metabolite (N-desalkylpropafenone)

Citation: Zhou Q, Yao TW, Zeng S. Chiral metabolism of propafenone in rat hepatic microsomes treated with two inducers. World J Gastroenterol 2001; 7(6): 830-835
URL: https://www.wjgnet.com/1007-9327/full/v7/i6/830.htm
DOI: https://dx.doi.org/10.3748/wjg.v7.i6.830