Copyright
©The Author(s) 2001.
World J Gastroenterol. Dec 15, 2001; 7(6): 805-810
Published online Dec 15, 2001. doi: 10.3748/wjg.v7.i6.805
Published online Dec 15, 2001. doi: 10.3748/wjg.v7.i6.805
Table 2 Pathological germ-line mutations in the hMLH1 and hMSH 2 genes
| Family | Gene | Exon | Codon | Mutation | Nucleotide Change |
| H2 | hMSH2 | 13 | 680 | Nonsense | CGA-TGA (stop codon) |
| H9 | hMLH1 | 11 | 305 | In-frame deletion | 24 bp deletion |
| H27 | hMSH2 | 3 | 206 | Frame shift | 1 bp (A) insertion; stop at 73 bp downstream of the mutation |
- Citation: Cai Q, Sun MH, Lu HF, Zhang TM, Mo SJ, Xu Y, Cai SJ, Zhu XZ, Shi DR. Clinicopathological and molecular genetic analysis of 4 typical Chinese HNPCC families. World J Gastroenterol 2001; 7(6): 805-810
- URL: https://www.wjgnet.com/1007-9327/full/v7/i6/805.htm
- DOI: https://dx.doi.org/10.3748/wjg.v7.i6.805