Telomere erosion is independent of microsatellite instability but related to loss of heterozygosity in gastric cancer

Figure 4 Representative LOH analysis of APC, MCC and DCC genes. (APC: Rsa1 RFLP in APC exon 11, loss of 133 bp allele is seen in tumor DNA, MCC: A 14 bp insertion/deletion polymorphism in MCC exon 10 gives rise to a 93 or 79 allele. Loss of the 93 bp allele is seen in the tumor. DCC: Losses of 396 bp, 240 bp and 200 bp alleles are seen at M2, M3 and VNTR polymorphic sequences in the tumor DNA)