Adjuvant therapy in pancreatic cancer

Table 2 Survival following surgery and radiotherapy for pancreatic cancer

Series	Year	Number	EBRT (Gy)	IORT (Gy)	Median survival (months)	Actuarial survival (%)
						1 year	3 year	5 year
Willett et al[32]	1993	16 (nm)	40-50		21			29
		23 (pm)	40-50		11			0
Johnstone et al[53]	1993	26	45-55	20	18
Zerbi et al[21]	1994	43		12.5-20	19	71	7
		47			12	49	10
Di Carlo et al[54]	1997	27			14
		27		12.5-2017
Dobelbower et al[55]	1997	14			6.5	15	0	0
		6		10-20	9	50	35	33
		14	50-67		14.5	64	28	0
		10	27-54	10-25	18	70	10	0
Farrell et al[56]	1997	14	60	12-25	16	62	22	15
Hishinuma et al[57]	1998	34	24 EBRT	13 EBRT + IOR	13	59		19
Klinkenbijl et al*[58]	1999	54pdc			12.6			10
		60pdc	40		17.1			20
Mehta et al[59]	2000	52	45-54	8 IORT	32	75	38
Lee et al[60]	2000	22					47
		13	49				81

EBRT = external beam radiotherapy; IORT = intraoperative radiotherapy; nm = negative resection margin; pm = positive resection margin; pdc = pancreatic ductal adenocarcinoma.