Inhibitory effects of RRR-α-tocopheryl succinate on benzo(a)pyrene (B(a)P)-induced forestomach carcinogenesis in female mice

Table 2 Inhibitory effects of VES on B(a)P induced forestomach tumorgenesis (x^-± s_x-)

Groups	No.of mice	Body weight (g)	Total tumors
			Tumors/mouse	% of mice with tumors
1. Succinic acid	12	39.5 ± 1.58	0	0
2. Succinic acid + B(a)P	9	40.2 ± 1.12	5.3 ± 0.48	100
3. B(a)P	10	40.6 ± 1.14	5.4 ± 0.32	100
4. 1.25 g/kgVES + B(a)P	11	40.1 ± 1.22	1.7 ± 0.41a (68.5)	81.8 (18.2)
5. 2.5 g/kgVES + B(a)P	13	39.9 ± 1.66	1.6 ± 0.34a	76.9 (23.1)
6. 20 mg/kgVES(ip) + B(a)P	10	38.7 ± 1.06	1.1 ± 0.43a (79.6)	50.0 (50.0)

^aCompared with B(a)P group (group 3), P < 0.05 (using Student t test) Numbers in parentheses are % of inhibition compared to group 3.