Animal experiment and clinical study of effect of gamma-interferon on hepatic fibrosis

Table 4 Serum hyaluronic acid level and liver hydroxylproline content in DMN-induced specimens after 4-weeks treatment

Groups	HA (μg/L)	Hyp (mg/g liver dry weight)
Normal control group	147.64 ± 19.28	2.43 ± 0.33
Fibrotic model group	969.52 ± 257.80	12.79 ± 1.54
Colchicine treatment group	323.72 ± 388.45a	6.40 ± 1.84a
High-dose IFN-γ group	144.25 ± 105.66	2.72 ± 0.58
Medium-dose IFN-γ group	334.10 ± 420.06	3.14 ± 0.71
Low-dose IFN-γ group	407.95 ± 386.61a	3.62 ± 1.02bd

^aP < 0.05 vs fibrotic model group;

^bP < 0.01 vs fibrotic model group; ^cP < 0.05 vs colchicines treatment group;

^dP < 0.01 vs colchicines treatment group.