Animal experiment and clinical study of effect of gamma-interferon on hepatic fibrosis

Table 2 Histological grading and staging in DMN-induced specimens after 4 week treatment

Groups	2g*	2s*	SSS△
Normal control group	1.00 ± 0.00	1.00 ± 0.00	0
Fibrotic model group	7.00 ± 2.16	9.60 ± 4.70	12.60 ± 3.57
Colchicine treatment group	6.80 ± 4.13	7.00 ± 3.92a	11.30 ± 2.37a
High-dose IFN-γ group	6.40 ± 2.07	2.60 ± 0.97bc	6.30 ± 0.48bc
Medium-dose IFN-γ group	4.80 ± 2.35	4.00 ± 2.32bc	8. 10 ± 2.72bc
Low-dose IFN-γ group	5.00 ± 2.71	4.40 ± 2.07bc	8.30 ± 2.58bc

*Scheuer’s criteria;

^△Chevallier’s criteria;

^aP < 0.05 vs fibrotic model group;

^bP < 0.01 vs fibrotic model group;

^cP < 0.05 vs colchicines treatment group.