Humoral and cellular immunogenecity of DNA vaccine based on hepatitis B core gene in rhesus monkeys

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Feb 15, 2001 (publication date) through Jul 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 15, 2001; 7(1): 102-106
Published online Feb 15, 2001. doi: 10.3748/wjg.v7.i1.102

Table 4 HBcAg specific PBMC proliferation activity*

Monkey No.	Group	HBcAg dose for stimulation (μg/well)
Monkey No.	Group	0	5	10	12.5
2	Experimental	354.4 ± 64.5	984.9 ± 105.4^a (2.74)	1364.9 ± 47.9^a (3.83)	890 ± 155.6^a (2.12)
3	Control	198.4 ± 3.9	274.5 ± 33.2 (1.37)	261.5 ± 28.2 (1.32)	250 ± 70.0 (1.24)

*The values in the table refer to CPM (x^-± s from each triplicate well), the values in the brackets indicate stimulation index (SI).

^aP < 0.05 vs control monkey.

Citation: Huang ZH, Zhuang H, Lu S, Guo RH, Xu GM, Cai J, Zhu WF. Humoral and cellular immunogenecity of DNA vaccine based on hepatitis B core gene in rhesus monkeys. World J Gastroenterol 2001; 7(1): 102-106
URL: https://www.wjgnet.com/1007-9327/full/v7/i1/102.htm
DOI: https://dx.doi.org/10.3748/wjg.v7.i1.102