Microsatellite instability, MMR gene expression and proliferation kinetics in colorectal cancer with famillial predisposition

Table 2 MSI and location, histologic differentiation of colorectal cancer

Group	MSI	Location n (%)		Differentiation n (%)
		Pr	Di	PD	WD
A	+	8 (66.7)	4 (33.3)	9 (75.0)b	3 (25.0)
	-	5 (35.7)	9 (64.3)	4 (28.6)	10 (71.4)
B	+	1 (50.0)	1 (50.0)	2	0
	-	4 (22.2)	14 (77.8)	5 (27.8)	13 (72.2)
Total	+	9 (64.3)a	5 (35.7)	11 (78.6)a	3 (21.4)
	-	9 (28.1)	23 (71.9)	9 (28.1)	23 (71.9)

^aP < 0.05, vs patients negative for MSI; χ² test.

^bP < 0.05, vs patients negative for MSI in Group A; χ² test. Pr: proximal colon; Di: distal colon (descending, sigmoid colon and rectum); PD: poorly differentiated adenocarcinoma; WD: well and moderately differentiated adenocarcinoma.