Effect of Boschniakia rossica on expression of GST-P, p53 and p21ras proteins in early stage of chemical hepatocarcinogenesis and its anti-inflammatory activities in rats

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Dec 15, 2000 (publication date) through Jul 28, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Dec 15, 2000; 6(6): 812-818
Published online Dec 15, 2000. doi: 10.3748/wjg.v6.i6.812

Table 5 Effect of BR-H₂O extract on adjuvant arthitis in rats

Groups	Dose (mg/kg)	Rats (n)	Swelling degree (inhibitory rate)
Groups	Dose (mg/kg)	Rats (n)	18 h	3d	6d	9d	12d	15d	18d	21d	24d
NS		6	108.2 ± 43.8	74.7 ± 33.0	66.9 ± 47.9	58.0 ± 39.0	77.8 ± 39.6	77.1 ± 28.0	99.6 ± 34.9	78.6 ± 31.3	71.5 ± 28.7
			108.2 ± 43.8	74.7 ± 33.0	66.9 ± 47.9	58.0 ± 39.0	77.8 ± 39.6	77.1 ± 28.0	99.6 ± 34.9	78.6 ± 31.3	71.5 ± 28.7
BR	500	6	79.1 ± 22.3^b	33.9 ± 17.2^a	51.8 ± 25.0	52.6 ± 23.7	67.5 ± 21.1	75.7 ± 23.7	61.7 ± 19.0^a	53.4 ± 14.9^b	46.5 ± 17.2^b
			79.1 ± 22.3^b	33.9 ± 17.2^a	51.8 ± 25.0	52.6 ± 23.7	67.5 ± 21.1	75.7 ± 23.7	61.7 ± 19.0^a	53.4 ± 14.9^b	46.5 ± 17.2^b
			(26.9)	(54.7)	(22.6)	(9.3)	(13.2)	(1.8)	(38.1)	(32.1)	(35.0)

^aP < 0.05;

^bP < 0.01, vs NS (t test), NS: normal saline; Ind: indomethacin; BR:Boschniakia rossica

Citation: Yin ZZ, Jin HL, Yin XZ, Li TZ, Quan JS, Jin ZN. Effect of Boschniakia rossica on expression of GST-P, p53 and p21^ras proteins in early stage of chemical hepatocarcinogenesis and its anti-inflammatory activities in rats. World J Gastroenterol 2000; 6(6): 812-818
URL: https://www.wjgnet.com/1007-9327/full/v6/i6/812.htm
DOI: https://dx.doi.org/10.3748/wjg.v6.i6.812