Effect of Boschniakia rossica on expression of GST-P, p53 and p21ras proteins in early stage of chemical hepatocarcinogenesis and its anti-inflammatory activities in rats

Table 4 Inhibitory effect of BR-H₂O extract on carrageenin-induced paw edema in rats (¯x ± s)

Groups	Dose (mg/kg)	Rats (n)	Swelling degree (inhibitory rate)
			1 h	2 h	3 h	4 h	6 h	24 h
NS		9	39.5 ± 16.4	57.1 ± 19.3	63.6 ± 26.1	67.9 ± 22.6	67.5 ± 19.5	28.2 ± 13.0
Ind	20	9	25.9 ± 13.8	30.6 ± 19.2a	32.6 ± 18.6a	38.6 ± 22.1a	42.2 ± 34.6	16.9 ± 12.3
			(34.2)	(46.5)	(47.2)	(43.1)	(37.5)	(39.9)
BR	500	9	30.6 ± 13.8	28.7 ± 8.3b	39.4 ± 12.2a	40.1 ± 14.2a	39.5 ± 20.0a	9.6 ± 8.5b
			(22.7)	(49.8)	(38.0)	(36.2)	(41.5)	(65.8)
BR	1000	9	31.8 ± 15.7	26.3 ± 18.9b	36.5 ± 19.9a	37.0 ± 288a	23.5 ± 16.4c	6.8 ± 10.4b
			(19.6)	(54.0)	(40.6)	(45.5)	(65.2)	(76.5)

^aP < 0.05;

^bP < 0.01;

^cP < 0.001, vs NS (t test)