Effect of Boschniakia rossica on expression of GST-P, p53 and p21ras proteins in early stage of chemical hepatocarcinogenesis and its anti-inflammatory activities in rats

Table 3 Effect of BR-extract on Croton oil-induced mouse ear edema

Groups	Dose (mg/kg)	Mouse (n)		BR-H2O fraction (I)		BR-CH2Cl2 fraction (II)
		I	II	Edema degree (mg)	Inhibitory rate (%)	Edema degree (mg)	Inhibitory rate (%)
NS (A)	0.85%	10	12	8.6 ± 2.5*		7.6 ± 3.3
Ind (B)	20	10	12	6.6 ± 4.0a	23.3	5.0 ± 2.1a	33.5
BR (C)	500	10	12	5.4 ± 3.4b	45.3	4.9 ± 1.7a	35.1
BR (D)	1000	10	12	4.7 ± 1.7c	59.3	4.5 ± 2.8a	40.0

^aP < 0.05;

^bP < 0.01;

^cP < 0.001; vs A (t test); NS: normal saline; Ind:indomethacin; BR: Boschniakia rossica