Effect of Boschniakia rossica on expression of GST-P, p53 and p21ras proteins in early stage of chemical hepatocarcinogenesis and its anti-inflammatory activities in rats

Table 1 Effect of Boschniakia rossica on the expression of GST-P, p53 and p21 protein in early stages of rat chemical hepatocarcinogenesis

Groups	Treatment (8 wk)	n	GST-P positive (%)	No.of foci (No/cm2)*	Area of foci (mm2/cm2)*	p53 positive (%)	p21 positive (%)
A	Saline-BD-PH	10	Negative	0	0	Negative	Negative
B	DEN-AAF-PH	9	7 (77.8)	18.9 ± 1.54	0.27 ± 0.32	3 (33.3)	2 (22.2)
C	DEN-AAF-BR-PH	10	2 (20.0)a	0.30 ± 0.67b	0.03 ± 0.07a	Negative	Negative

^aP < 0.05, vs B (χ² test); P < 0.05,

^bP < 0.01, vs B (t test).

^*Foci more than 0.1 nm in diameter were quantified; ^△Values ¯x ± s