Effect of arsenic trioxide on human hepatoma cell line BEL-7402 cultured in vitro

Figure 3 Scanning electronmicroscopic observation of changes in human hepatoma cell membranes treated with 0, 0. 5, 1, 2 μmol/L As₂O₃ for 96 h. There were abundant processes and micro villi on the surface of BEL-7402 cells in 0 μmol/L As₂O₃ group (A). The processes and micro villi was much less in 0.5 μmol/L As₂O₃ group (B). The processes and micro villi were lost when treated with 1, 2 μmol/L As₂O₃ (C, D).