A study on &alpha;-ketoadipic aciduria by gas chromatographic-mass spectrometry

doi:10.3748/wjg.v6.i5.766

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Oct 15, 2000 (publication date) through Nov 19, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 15, 2000; 6(5): 766-769
Published online Oct 15, 2000. doi: 10.3748/wjg.v6.i5.766

Table 1 Urinary concentrations of metabolites

Cases	Detecting age	α-KA	α-AA	α-HAA	Glutarate	Total value of metabolites
1	1.4 yrs	33 (ND)	223 (2-25)	28 (ND)	29 (0.04)	313
	4.2 yrs	33 (ND)	266 (0-51)	17 (ND)	24 (0.04)	340
	15 yrs	33 (ND)	92 (0-4)	21 (ND)	53 (ND)	199
2	13 d	31 (ND)	200 (1-11)	12 (ND)	9 (0.03)	252
	29 d	49 (ND)	450 (5-197)	17 (ND)	54 (0.03)	570
	5 yrs	9 (ND)	92 (0-4)	55 (ND)	216 (ND)	372
Average		31.3	220.5	25	64.2

Values are expressed as mmol/mol creatinine. (): Control. α-AA: α-aminoadipate, α-KA: α-ketoadipate, α-HAA: α-hydroxyadipate, ND: Not detected; d: Days, yrs: Years

Citation: Xia ZW, Inoue Y, Ohse M, Shinka T, Kuhara T. A study on α-ketoadipic aciduria by gas chromatographic-mass spectrometry. World J Gastroenterol 2000; 6(5): 766-769
URL: https://www.wjgnet.com/1007-9327/full/v6/i5/766.htm
DOI: https://dx.doi.org/10.3748/wjg.v6.i5.766