Alterations in gastric mucin synthesis by Helicobacter pylori

Figure 10 Effect of inhibitors of mucin synthesis on H. pylori adhesion. BG C-823 cells were treated with 2 mmol/L benzyl-GalNAc, with 5 μmol/L MUC1 antisense (5’-GGG-CTG-GGG-GGG-CGG-TGG-3’), or with 5 μmol/L MUC5AC antisense (5’-AGA-GGT-TGT-GCT-GGT-TGT-3’). Solid bars show, as percent of control, amo unts of total mucin (left), MUC1 mucin (middle), and MUC5AC mucin (right). Open bars show binding of biotinylated H.pylori, expressed as percent of control .