Alterations in gastric mucin synthesis by Helicobacter pylori

Figure 7 Effect of H. pylori on synthesis of peipheral and core carbohydrat e structures of mucin. KATO III cells were incubated with or without 2 mmol/L b enzy l-GalNAc, and labeled for 4 h in the presence or absence of 1 OD600 H.pylori . Bars show void volume (Vo) containing labeled mucin. Solid areas show labeli ng of the peripheral carbohdyrate (inhibitable by benzyl-GalNAc). Open areas sh ow residual labeling of core structures in the presence of benzyl-GalNAc.