Lactosamination of liposomes and hepatotropic targeting research

doi:10.3748/wjg.v6.i4.593

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Aug 15, 2000 (publication date) through Oct 6, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 15, 2000; 6(4): 593-596
Published online Aug 15, 2000. doi: 10.3748/wjg.v6.i4.593

Table 1 Tissue distribution of ¹³¹I-labeled L-HSA-liposomes in rat

Rat No.	*Tissue distribution in vivo* (cpm per gram tissue)**
Rat No.	Liver	Spleen^a	Kidney^b	Heart^c	Lung^d
1	31777.2	15394.2	7912.1	4427.5	9568.5
2	30476.1	15464.1	5424.5	3180.8	6044.1
3	30013.1	14041.4	7932.3	3777.5	5886.1
4	36099.3	10817.5	6372.3	3722.7	8717.3
5	36479.8	17882.6	7228.6	3885.5	7695.8
Average	32969.1	14719.9	6974.1	3798.8	7582.4

¹³¹I labeled L-HSA-liposomes were injected into rats. Radioactivity in different tissues was determined 40 min after injection as described in Materials and Methods. Compared with liver:

^aP = 7.84 × 10^-6;

^bP = 1.06 × 10^-7;

^cP = 2.98 × 10^-8;

^dP = 2.1 × 10^-7

Citation: Chen YP, Zhang L, Lu QS, Feng XR, Luo KX. Lactosamination of liposomes and hepatotropic targeting research. World J Gastroenterol 2000; 6(4): 593-596
URL: https://www.wjgnet.com/1007-9327/full/v6/i4/593.htm
DOI: https://dx.doi.org/10.3748/wjg.v6.i4.593