A 12-year cohort study on the efficacy of plasma-derived hepatitis B vaccine in rural newborns

Table 1 Dynamic change of anti-HBs positive rate and GMT after vaccination

Years vaccinated	Mothers HBsAg (-)			Mothers HBsAg (+)
	NO. tested	Positive rate (%)	GMT (S/N)	NO. tested	Positive rate (%)	GMT (S/N)
1	18	94.44	26.30	19	84.21	15.14
2	134	89.55	31.62	48	95.83	23.99
3	232	89.22	26.30	51	92.16	22.91
4	344	85.17	18.62	51	73.33	6.46
6	296	79.39	9.77	54	79.63	8.71
7	608	80.76	9.33	58	86.21	7.78
8	599	78.30	6.17	56	75.00	5.25
9	517	57.79	4.17	48	60.24	3.47
10	412	50.24	3.09	23	34.78	2.51
11	173	51.80	2.86	30	56.00	2.91
12	424	51.30	3.13	20	52.50	3.65
χ2-m-h		226.12			338.58
P value		P < 0.001			P < 0.001