Analysis of in vivo patterns of caspase 3 gene expression in primary hepatocellular carcinoma and its relationship to p21WAF1 expression and hepatic apoptosis

Table 1 Correlation between clinicopathological parameters and expression of caspase 3 in HCCs

	No.	Caspase 3 expression (%)	P
Samples
Non-cancerous adjacent liver	8	7 (87.5)	< 0.05
HCC	39	21 (53.8)
Age (year)
< 60	28	15 (53.6)	NS
> 60	11	6 (54.5)
Sex
Male	34	18 (52.9)	NS
Female	5	3 (60.0)
Tumor size (cm)
> 5.0	27	15 (55.6)	NS
< 5.0	12	6 (50.0)
Differentiation
Well-moderate	18	13 (72.2)	< 0.05
Poor	21	8 (38.1)
TNM grade
I-II	21	12 (57.1)	NS
III-IV	18	9 (50.0)
Metastasis
Negative	31	16 (51.6)	NS
Positive	8	5 (62.5)
p21WAF1
Positive	23	16 (69.6)	< 0.05
Negative	16	5 (31.3)

NS: No statistic significance