Susceptibility to hepatocellular carcinoma associated with null genotypes of GSTM1 and GSTT1

Table 4 The relationship between different exposure levels of GSTM1, GSTT1 and HCC

Exposure level		Cases		Control		OR
GSTM1	GSTT1	n	%	n	%
-	-	1	1.6	16	18.2	1.00
+	-	7	11.1	17	19.3	6.59
-	+	26	41.3	35	39.8	11.89
+	+	29	46.0	20	22.7	23.20
Total		63	100.0	88	100.0

χ²_trend = 16.413, P = 0.000051. GSTM1 (+): GSTM1 null genotype, (-): non null genotype. GSTT1 (+): GSTT1 non null genotype, (-): null genotype.