Chronic ulcerative colitis model in rats

Figure 2 Histological findings in ulcerative colitis induced by different doses of TNBS ethanol. a: TNBS 25 mg/kg, the mucosa is normal. b: TNBS 50 g/kg, small mucosal ulc ers and cryptoabscess formation. c-d: TNBS 100 mg/kg, mucosal ulcers, in flammatory exudate, proliferous granulomas and cells infiltration. e-f: TNBS 150 g/kg, gross ulcers and proliferous granulomas, necrosis of epithelium at mu cosal sueface and inflammatory cell infiltration (He, × 100)