Update of preclinical and human studies of calcium and colon cancer prevention

Table 2 Dietary calcium effects on epithelial cells in the colon and other organs of rodents

Cell proliferation	References*
Calcium decreased hyperproliferation Gover et al 1994
Calcium: decreased hyperproliferation when induced by doxycholic acid	Wargovich et al 1983
Decreased hyperproliferation when induced by fatty acids	Wargovich et al 1984
Decreased hyperproliferation when induced by cholic acid	Bird et al 1986
Decreased hyperproliferation induced by partial enteric resection	Appleton et al 1986
Decreased deoxycholic acid-induced hyperproliferation	Hu et al 1989
Decreased MNNG-induced hyperproliferation on diet low in fat and calcium	Reshef et al 1990
Decreased hyperproliferation induced by Western-style diet	Newmark et al 1991
Decreased AOM-induced ODC and Tyr K	Arlow et al 1989
Decreased ODC induced by bile acids	Baer et al 1989
Decreased hyperproliferation when induced by Western-style diet	Richter et al[24] 1995
Decreased hyperproliferation in other organs when induced by Western-style diet	Xue et al[25] 1999

*Studies without reference numbers are found in[23].