Expression of B7 costimulation molecules by colorectal cancer cells reducestumorigenicity and induces anti-tumor immunity

Figure 5 Protective immunity. ■In control group, four native mice injected 2.5 × 10⁶ wild type CMT93 cells, one mouse’s tumor vanished. Three mice’s tumor grew progressively. ●In experimental group, four mice primed with CMT93-B7 were rechallenged with 2.5 × 10⁶ wild type CMT93 cell, and no tumors were found. (P < 0.05 compared with control group).