Chemoprevention of 2-amino-1-methyl-6-phenyli-midazo [4, 5-b] pyridine-induced carcinogen-DNA adducts by Chinese cabbage in rats

Table 1 Effect of Chinese cabbage on glutathion S-transferase activity

Treatment groupa	GST activity (nmol/mg-1 protein-1/min)b
	Colon	Lung	Liver
Control diet + solvent	135 ± 19	60 ± 10	1842 ± 298
Control diet + PhIP	134 ± 26	73 ± 8	1871 ± 351
Cabbage diet + PhIP	142 ± 29	99 ± 9c	2212 ± 423c

^aAnimals were given a single dose of PhIP (10 mg/kg body wt) or its vehicle solvent after ten days on the diets. The cabbage diet was a basal diet containing 20% (w/w) freeze-dried Chinese cabbage powder.

^bGlutathion S-transferase activity towards CDNB (nmol/mg^-1 protein^-1/min) was determined in triplicate. Values given are ^-x±s.

^cP < 0.05 as compared to control diet + PhIP group (Student’s t test).