Copyright
©The Author(s) 1999.
World J Gastroenterol. Feb 15, 1999; 5(1): 57-60
Published online Feb 15, 1999. doi: 10.3748/wjg.v5.i1.57
Published online Feb 15, 1999. doi: 10.3748/wjg.v5.i1.57
Table 3 Distribution of 125I sodium alginate-BSA NP in rats (n = 3, dosage 148 × 108 Bq per rat, po.)
| Organ | Value of radioactive counting of 100mg tissue in 30s at different time points | |||||
| 1 h | 4 h | 8 h | 16 h | 24 h | 36 h | |
| Blood | 502 ± 100 | 601 ± 135 | 373 ± 22 | 298 ± 19 | 191 ± 17 | 129 ± 23 |
| Heart | 436 ± 110(0.86) | 801 ± 66(0.33) | 265 ± 23(0.71) | 230 ± 23(0.77) | 190 ± 10(0.99) | 87 ± 35(0.67) |
| Liver | 436 ± 110(0.86) | 908 ± 100(1.51) | 777 ± 69(2.08) | 405 ± 97(1.36) | 226 ± 16(1.18) | 153 ± 21(1.19) |
| Spleen | 663 ± 140(1.32) | 1029 ± 168(1.71) | 834 ± 272(2.32) | 436 ± 195(1.46) | 233 ± 25(1.22) | 169 ± 27(0.95) |
| Lungs | 717 ± 314(1.42) | 818 ± 172(1.36) | 597 ± 121(1.60) | 443 ± 31(1.49) | 166 ± 4(0.87) | 119 ± 27(0.92) |
| Kidneys | 526 ± 139(1.05) | 185 ± 39(0.14) | 401 ± 71(1.08) | 387 ± 105(1.30) | 133 ± 13(0.69) | 123 ± 14(0.95) |
| Brain | 105 ± 31(0.21) | 112 ± 49(0.19) | 111 ± 47(0.30) | 96 ± 27(0.32) | 50 ± 5(0.26) | 39 ± 11(0.30) |
| Stomach | 89654 ± 7143 | 28674 ± 3647 | 8362 ± 1902 | 4641 ± 1400 | 698 ± 34 | 527 ± 114 |
| Intestine | 765 ± 137 | 5573 ± 891 | 30 ± 599 | 403 ± 118 | 115 ± 64 | 204 ± 46 |
| Bowel | 1256 ± 664 | 639 ± 1023 | 30 ± 599 | 3221 ± 863 | 125 ± 60 | 256 ± 102 |
- Citation: Yi YM, Yang TY, Pan WM. Preparation and distribution of 5-fluorouracil 125I sodium alginate-bovine serum albumin nanoparticles. World J Gastroenterol 1999; 5(1): 57-60
- URL: https://www.wjgnet.com/1007-9327/full/v5/i1/57.htm
- DOI: https://dx.doi.org/10.3748/wjg.v5.i1.57