Persistence of hepatitis B vaccine immune protection and response to hepatitis B booster immunization

Table 2 Comparison of anti-HBs level before and after hepatitis B booster in 144 subjects immunized with hepatitis B vaccine

Time point of observation	No. of subjects	Anti-HBs (mIU/mL)
		< 10		≥ 10		≥ 100		≥ 1000		GMT	t	P
		n	%	n	%	n	%	n	%
Before booster	144	65	45.1	58	40.3	20	13.9	1	0.7	10.4
One month after booster	144	15	10.4	16	11.1	100	69.4	13	9.0	190.6	17.4	< 0.01
12 months after booster	106*	26	24.5	43	40.6	33	31.1	4	3.8	25.3	1.3	> 0.05

^* blood specimens only collected from 106 children in the 12th month after booster.