Interaction between cisplatin, 5-fluorouracil and vincristine on human hepatoma cell line (7721)

Table 2 Fa and CI of drug combinations at different ratios

Drug 1 (mg/L)		Drug 2 (mg/L)		fa	CI	Drug 1 (mg/L)		Drug 2 (mg/L)		fa	CI
Cis	2.5	5-Fu	100	0.821	0.75	Cis	2.5	VCR	2	0.554	1.15
	5		100	0.856	0.85		5		2	0.858	0.80
	10		100	0.877	0.87		10		2	0.862	0.74
	20		100	0.883	1.09		20		2	0.873	0.71
	40		100	0.893	1.23		40		2	0.904	0.66
Cis	2.5	5-Fu	200	0.839	1.85	VCR	0.25	5-Fu	100	0.657	2.39
	5		200	0.867	2.93		0.5		100	0.761	1.15
	10		200	0.899	2.95		1		100	0.810	0.77
	20		200	0.902	3.00		2		100	0.826	0.64
	40		200	0.907	3.36		4		100	0.850	0.51
Cis	2.5	VCR	1	0.498	0.32	VCR	0.25	5-Fu	200	0.759	2.13
	5		1	0.825	1.38		0.5		200	0.783	1.79
	10		1	0.844	2.05		1		200	0.825	1.28
	20		1	0.852	2.09		2		200	0.839	1.10
	40		1	0.894	3.40		4		200	0.867	0.92