Changes of lipid metabolism in plasma, liver and bile during cholesterol gallstone formation in rabbit model

Table 2 The results of hepatic and biliary cholesterol and bile acids

	Control	Experimental groups
		1 wk	2 wk	3 wk	4 wk
TCd	25.02 ± 6.21	33.63 ± 16.86a	36.23 ± 8.31a	65.75 ± 33.41ab	83.87 ± 35.10abc
TGd	158.72 ± 58.15	145.37 ± 21.34	142.27 ± 30.24	148.22 ± 38.16	151.52 ± 35.52
PLd	29.21 ± 7.04	34.65 ± 7.56	30.23 ± 10.16	29.02 ± 10.89	27.81 ± 9.53
GDCAe	275.35 ± 101.46	532.83 ± 258.71	413.73 ± 132.37	393.54 ± 108.71	348.14 ± 132.71
GCAe	97.81 ± 59.28	87.56 ± 59.52	73.26 ± 49.54	58.61 ± 9.89a	43.79 ± 38.74a
CHf	2.51 ± 1.36	3.58 ± 1.98	3.85 ± 1.41	4.32 ± 1.23a	5.02 ± 1.86a

^aP < 0.05, vs Con;

^bP < 0.05, vs 1, 2 wk;

^cP < 0.05, vs 3 wk;

^dHepatic TC, TG and PL (mg/g);

^eBile GDCA and GCA (mg/L);

^fBile cholesterol (mol/L).