Editorials
Copyright ©The Author(s) 1998.
World J Gastroenterol. Aug 15, 1998; 4(4): 280-284
Published online Aug 15, 1998. doi: 10.3748/wjg.v4.i4.280
Table 2 Pathophysiologic factors contributing to the development of reflux
Incompetent lower esophageal sphincter
Low pressure sphincter
Short sphincter length
Poor esophageal peristalsis
Decreased amplitude of contractions
Absence of propagated peristalsis
Delayed gastric emptying
Inadequate gastric contractions
Partial gastric outlet obstruction
Mucosal susceptablity to refluxate
Acid
Pepsin
Bile
Duodenal fluid