Effects of erythromycin on pressure in pyloric antrum and plasma motilin and somatostain content in dogs

Table 1 Pyloric pressure and plasma MTL and SS content before and after infusion of erythromycin in dogs. (n = 10, x^-±s)

Parameters	Before drug administration	Erythromycin	Verapamil	Atropine
Total pressure (kPa)	20.1 ± 2.2	34.5 ± 3.1a	10.3 ± 0.4a	8.2 ± 0.2a
Basic pressure (kPa)	4.1 ± 2.5	6.9 ± 0.9a	4.4 ± 0.8	5.2 ± 0.2
Wave amplitude pressure (kPa)	16.0 ± 14.4	27.6 ± 9.6a	5.9 ± 0.4a	3.0 ± 0.1b
Wave frequency (time/min)	9.8 ± 4.5	5.4 ± 0.5a	2.9 ± 0.4a	2.0 ± 1.0b
Wave interval (s)	3.0 ± 1.1	6.7 ± 0.6a	3.8 ± 0.4	3.1 ± 0.1
Plasma MTL (ng/L)	426.9 ± 53.4	553.9 ± 87.2a	447.9 ± 67.6	378.3 ± 8.2a
Plasma SS (ng/L)	64.6 ± 13.7	75.2 ± 4.7a	85.6 ± 2.9b	105.6 ± 0.2b

^aP < 0.05,

^bP < 0.01 vs before used medicine.