Codon 249 mutations of p53 gene in development of hepatocellular carcinoma

Figure 1 Examination of codon 249 mutation using RFLP analysis. Lane 1 and lane 2 were PCR products from cancerous tissues without and with digestion of restriction enzyme Hae III. Lane 3 and lane 4 were products from pericancerous tissues with and without digestion of restriction enzyme Hae III. Lane 5 was marker of 100 bp ladder from GIBco BRL.