Beyond the tumor region: Peritumoral radiomics enhances prognostic accuracy in locally advanced rectal cancer

Figure 5 Relative importance weight of variables in integrated clinical-radiological-omics model. The relative importance weight of a variable was calculated using the permutation feature importance by measuring the change in the model’s C-index after random shuffling of each feature value, with the importance scaled relative to the maximum observed change. BMI: Body mass index; GLCM: Grey level co-occurrence matrix; GLDM: Grey level dependence matrix; GLSZM: Grey level size zone matrix; HHH: High-high-high; HHL: High-high-low; HLH: High-low-high; LHL: Low-high-low; LLH: Low-low-high; LLL: Low-low-low; MRF: Mesorectal fascia; NGTDM: Neighboring grey tone difference matrix; TRG: Tumor regression grade; ypN stage: Pathological N stage after neoadjuvant chemoradiotherapy.