New frontiers in hepatocellular carcinoma: Precision imaging for microvascular invasion prediction

Table 3 Independent risk factors for microvascular invasion and high-risk group[1]

Prediction target	Risk factor	Odds ratio (95%CI)	P value
MVI status	Non-smooth tumor margin	2.655 (1.241-5.679)	0.012
	Absence of peritumoral hypointensity ring	5.360 (1.857-15.477)	0.002
	Radscore (ROI tumor-DP)	6.552 (3.364-12.761)	< 0.001
M2 status	AFP level	3.818 (1.380-10.563)	0.01
	Enhancing capsule	3.962 (1.628-9.643)	0.002
	AST level	3.760 (1.485-9.520)	0.005
	Radscore (ROI peri-AP)	5.967 (2.609-13.649)	< 0.001

MVI: Microvascular invasion; AUC: Area under the curve; AFP: Alpha-fetoprotein; AST: Aspartate aminotransferase; ROI ^tumor-DP: Region of interest of tumor from delayed phase; ROI ^peri-AP: Region of interest of peritumoral area from arterial phase. Citation: Xu ZL, Qian GX, Li YH, Lu JL, Wei MT, Bu XY, Ge YS, Cheng Y, Jia WD. Evaluating microvascular invasion in hepatitis B virus-related hepatocellular carcinoma based on contrast-enhanced computed tomography radiomics and clinicoradiological factors. World J Gastroenterol 2024; 30: 4801-4816.